Research Studies

Research on Autism and Related Developmental Disorders

The Developmental Disorders Genetics Research Program (DDGRP) at Bradley Hospital and Brown University is looking for genes involved in autism and related disorders, such as intellectual disability (formerly known as mental retardation). The DDGRP is directed by Dr. Eric M. Morrow who is a genetics researcher who specialized in developmental disorders. We are also trying to find whether autism occurs along with a chromosome problem, such as a chromosomal deletion. Families are invited to ask about participation in our study searching for the genes that lead to autism and related disorders. We hope that by finding these genes we will better understand both normal and abnormal brain development.

Participation in our research involves providing a DNA sample, usually by giving a small amount of blood (about two tablespoons) and/or saliva, as well as sharing information about medical and family history. Details we ask for include copies of MRI images and medical records. We request DNA samples from affected individuals as well as their parents and healthy siblings, when possible. Reading and signing a research consent form is required before participating.

General results of our study are made available through scientific publications when the study is complete. Because research can be a lengthy process, it may be a very long time before there are any results. It is also possible that we will be unable to identify the gene(s) causing some conditions and in these cases no results will be available. Participants will not be given the results of their individual testing. However, if there are research findings that may be of possible medical benefit, we can contact the referring doctor, with the family’s permission, to discuss the genetic information. Follow-up counseling and another blood draw for testing in a clinical laboratory may be suggested, though this may not be available free of charge.

For more information about our research or how to participate, please contact the research coordinator for the DDGRP at Bradley Hospital at 401‐863-9778 or email us at DDGRP@brown.edu. Please also visit our website: www.ddgrp.org.